Hpv oropharyngeal cancer presentation. Head and Neck Cancer: Management and Reconstruction

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Department of Ophthalmology, Grigore T. E-mail: moc.

We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.

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The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.

Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

Head and Neck Cancer: Management and Reconstruction, ORL - cysoft.ro

The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.

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Case Report We present a unique case of squamous cell carcinoma of hpv oropharyngeal cancer presentation conjunctiva examined and treated in June The year-old patient hpv oropharyngeal cancer presentation at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.

He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

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  • Tratamentul carcinoamelor de planşeu oral anterior

The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal.

Frequently, a mandible resection is required in order to obtain safe oncologic margins. The prognosis is good, with a higher overall survival rate than in other oral hpv oropharyngeal cancer presentation. Keywords carcinoma, floor of the mouth, mandible resection, neck dissection Rezumat Cu o prevalenţă inferioară tumorilor maligne ale limbii, tu­mo­ri­le maligne de planşeu anterior impun o abordare chi­rur­gi­ca­lă la fel de radicală, cu o margine de siguranţă mare şi cu ma­nage­mentul problemelor de la nivelul gâtului. Datorită lo­ca­li­ză­rii lor anterioare, sunt mai uşor de diagnosticat, iar pa­cien­tul se prezintă şi în stadii incipiente, nu doar în stadii tar­di­ve.

Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.

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  • Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva

The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using hpv oropharyngeal cancer presentation supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.

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Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.

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