Elizabeth Murchison studies a mysterious and contagious cancer that threatens to wipe out Tasmanian devils.
Why you should listen Elizabeth Murchison grew up aggressive cancer spread Tasmania, the island home of the small, aggressive marsupial known as the Tasmanian devil. In the mid-'90s, the devils were beset with a terrible new disease -- a contagious facial cancer, spread by biting, that killed the animals just as they reached breeding age.
Byhalf the devil population of Australia had contracted the cancer and died.
Analyzing gene and microRNA activity in 25 different facial tumors and in healthy tissue, the team found that cancers from animals across Tasmania were identical, and that the cancer stems from Schwann cells, which normally insulate nerve fibers.
Now a Research Fellow in Medical Sciences at King's College, Aggressive cancer spread, Murchison is using high-throughput DNA sequencing technologies to investigate the genetics and evolution of this disease, one of only three known cancers that spread contagiously.
She says: "This is why cancer is such a difficult disease to treat: It evolves.